A two-week cinaciguat study restored features of aging liver cells in rats and halved blood amyloid beta. Human effects are unknown.

A Tiny Buddha contributor describes why she stopped drinking, including blackouts, anxiety, family concerns and a changing view of social drinking.

A Norwegian analysis of 2,252 patients found no significant 12-month disability benefit from adding spinal fusion to decompression surgery.

A study using data from nearly 2.8 million people identified 127 Alzheimer’s risk loci and found that common-variant heritability estimates depend on the method used.

A Swedish cohort study found higher type 1 diabetes risk among children whose parents had autoimmune disease, with the strongest associations for parental type 1.

Psychiatrist Devina Wadhwa argues that screening tools should not replace clinical judgment when grief, stress and psychiatric illness overlap.